Tag: Spinal Fusion
Role of Weekly Teriparatide Administration in Osseous Union Enhancement within Six Months After Posterior or Transforaminal Lumbar Interbody Fusion for Osteoporosis-Associated Lumbar Degenerative Disorders: A Multicenter, Prospective Randomized Study.
With the aging or a population, there has been significant increases in the number of patients receiving lumbar fusion operations secondary to spinal stenosis or spondylolisthesis with spinal stenosis. Unfortunately, bone quality has bearing on the success of lumbar fusions. This paper is a 6 month randomized prospective study on the use of weekly subcutaneous […]
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Decompression and Coflex interlaminar stabilization compared with decompression and instrumented spinal fusion for spinal stenosis and low-grade degenerative spondylolisthesis: two-year results from the prospective, randomized, multicenter, Food and Drug Administration Investigational Device Exemption trial.
By most definitions, this is a good example of a randomized control trial (RCT). The study populations were well matched and the outcomes were standardly measured. The follow-up rate was greater than 80%. The inclusion criteria included the presence of back pain (VAS of 5/10 or more), along with spinal stenosis and up to grade […]
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Surgery for spinal stenosis: long-term reoperation rates, health care cost, and impact of instrumentation.
There has been a significant increase in the rates of spinal fusion in the past 15 years in the United States. This study attempted to identify the efficacy and costs associated with this trend. This study by Lad et al provided a retrospective cohort analysis of a population that underwent spinal stenosis surgery between 2002 […]
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Radiculopathy and myelopathy at segments adjacent to the site of a previous anterior cervical arthrodesis.
This study by Hilibrand et al remains one of the most widely cited studies in regarding adjacent segment disease following anterior cervical discectomy and fusion. The study population of 374 consecutive patients (409 fusions) were followed prospectively for the development of adjacent segment disease, as defined by symptomatic radiculopathy or myelopathy, at an adjacent segment […]
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2001 Volvo Award Winner in Clinical Studies: Lumbar fusion versus nonsurgical treatment for chronic low back pain: a multicenter randomized controlled trial from the Swedish Lumbar Spine Study Group.
This multicenter, randomized control trial out of Sweden was the 2001 Volvo Award Winner in Clinical Studies. Fritzell et al randomized 294 patients into a surgical treatment group (n=222) versus a non-surgical group (N=72). Patients were randomly assigned treatment and multiple validated outcome measures were utilized. The overall goal of the study was to define “if lumbar fusion […]
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Accelerated degeneration of the segment adjacent to a lumbar fusion.
The study published by Lee in 1988 was intended to descriptively define conditions and pathomechanics at adjacent segments following a lumbar fusion. This was at a time period where the effectiveness of lumbar fusion for low back pain was one of the foremost questions to be answered and potential complications of the procedure were largely […]
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Degenerative lumbar spondylolisthesis with spinal stenosis. A prospective study comparing decompression with decompression and intertransverse process arthrodesis.
This study published by the late Dr. Harry Herkowitz, from William Beaumont Hospital in 1991, is one of the most influential papers of its time. His contributions to the field of degenerative spinal surgery continue to influence current research and treatment of many spinal disorders. This paper in particular, has been referenced over 800 times […]
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A prospective, randomized study of lumbar fusion. Preliminary results.
This randomized study published in 1993 was one of the first to compare instrumentation to no instrumentation using the prospective approach. One hundred and twenty four patients were included in this study who underwent surgery for a degenerative lumbar condition that included isthmic and degenerative spondylolisthesis, degenerative disc disease, scoliosis with spinal stenosis and repair […]
